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1.
J. coloproctol. (Rio J., Impr.) ; 41(4): 335-339, Out.-Dec. 2021. tab, graf
Article in English | LILACS | ID: biblio-1356437

ABSTRACT

Objective: To assess the survival rate of patients with colorectal cancer at Hospital Universitário Alzira Vellano, in the municipality of Alfenas, state of Minas Gerais (MG), Brazil, from 2007 to 2016. Methodology: A search was conducted in the laboratory files and medical records of patients diagnosed with colorectal cancer and cared for during the aforementioned period. Results: In total, 128 cases were found: 52.3% were men, and 47.7% were women, with ages ranging from 25 to 91 years. The most common types of cancer in both genders were of the colon, rectum and sigmoid. The most common stages were T3N1Mx, followed by T3N0Mx and T3N2Mx. Patients with T1 or T2 cancers had a 100% survival rate, whereas the rate for those with grade 4 (T4) was of 0%. An association (p<0.05) of the location of the tumor with the survival rate was confirmed. Conclusion: There was a high mortality rate among patients diagnosed with colorectal cancer at Hospital Universitário Alzira Vellano from 2007 to 2016. (AU)


Subject(s)
Humans , Male , Female , Adult , Middle Aged , Aged , Aged, 80 and over , Intestinal Neoplasms/mortality , Survival Rate
2.
Int. j. morphol ; 39(5): 1365-1370, oct. 2021. ilus, tab
Article in Spanish | LILACS | ID: biblio-1385499

ABSTRACT

RESUMEN: Los tumores neuroendocrinos (TNE) intestinales representan el mayor porcentaje de este tipo de lesiones a nivel del aparato digestivo. El tratamiento de elección es la extirpación de la lesión primaria y sus linfonodos regionales. El objetivo de este estudio es reportar el resultado de pacientes portadores de TNE intestinales, tratados quirúrgicamente, en términos de morbilidad postoperatoria (MPO) y mortalidad. Serie de casos de pacientes con TNE intestinales intervenidos de forma consecutiva en Clínica RedSalud Mayor Temuco, entre 2006 y 2020. Las variables resultado fueron MPO y mortalidad. Otras variables de interés fueron localización y diámetro del tumor, tipo de cirugía y estancia hospitalaria. Se utilizó estadística descriptiva. Se trató a 11 pacientes (54,5 % mujeres), con una mediana de edad de 56 años. El 54,5 % de los tumores se localizó en yeyuno-íleon. La mediana del diámetro tumoral, tiempo quirúrgico y estancia hospitalaria fueron 2 cm, 75 min y 4 días, respectivamente. El tipo de resección más frecuente fue hemicolectomía derecha (63,6 %). La MPO fue 9,1 % (seroma en un paciente). No hubo reintervenciones ni mortalidad operatoria. Con una mediana de seguimiento de 18 meses, no se verificaron recurrencias. Los resultados reportados en relación a MPO y mortalidad, son adecuados en relación con la evidencia publicada.


SUMMARY: Intestinal neuroendocrine tumors (INETs) represent the highest percentage of this type of lesion in the digestive system. The treatment of choice is removal of the primary lesion and its regional lymph nodes. The aim of this study is to report the results of patients with INETs treated surgically, in terms of postoperative morbidity (POM) and mortality. Series of cases of patients with intestinal INETs operated consecutively at Clínica RedSalud Mayor Temuco, between 2006 and 2020. Result variables were POM and mortality. Other variables of interest were location and diameter of the tumor, type of surgery, and hospital stay. Descriptive statistics were used. Eleven patients (54.5 %) were treated, with a median age of 56 years. 54.5 % of the tumors were located in the jejunum-ileum. The median tumor diameter, surgical time, and hospital stay were 2 cm, 75 min, and 4 days, respectively. The most frequent type of resection was right hemicolectomy (63.6 %). The MPO was 9.1 % (seroma in one patient). There were no reoperations or operative mortality. With a median follow-up of 18 months, there were no recurrences. Reported results in relation to POM and mortality are adequate in relation to the published evidence.


Subject(s)
Humans , Male , Female , Adult , Middle Aged , Aged , Neuroendocrine Tumors/surgery , Intestinal Neoplasms/surgery , Postoperative Complications , Follow-Up Studies , Treatment Outcome , Neuroendocrine Tumors/mortality , Neuroendocrine Tumors/pathology , Operative Time , Intestinal Neoplasms/mortality , Intestinal Neoplasms/pathology , Length of Stay
3.
Einstein (Säo Paulo) ; 13(4): 500-505, Oct.-Dec. 2015. tab, graf
Article in Portuguese | LILACS | ID: lil-770508

ABSTRACT

ABSTRACT Objective To characterize the pattern of primary small bowel cancers in a tertiary East-European hospital. Methods A retrospective study of patients with small bowel cancers admitted to a tertiary emergency center, over the past 15 years. Results There were 57 patients with small bowel cancer, representing 0.039% of admissions and 0.059% of laparotomies. There were 37 (64.9%) men, mean age of 58 years; and 72 years for females. Out of 57 patients, 48 (84.2%) were admitted due to an emergency situation: obstruction in 21 (38.9%), perforation in 17 (31.5%), upper gastrointestinal bleeding in 8 (14.8%), and lower gastrointestinal bleeding in 2 (3.7%). There were 10 (17.5%) duodenal tumors, 21 (36.8%) jejunal tumors and 26 (45.6%) ileal tumors. The most frequent neoplasms were gastrointestinal stromal tumor in 24 patients (42.1%), adenocarcinoma in 19 (33.3%), lymphoma in 8 (14%), and carcinoids in 2 (3.5%). The prevalence of duodenal adenocarcinoma was 14.55 times greater than that of the small bowel, and the prevalence of duodenal stromal tumors was 1.818 time greater than that of the small bowel. Obstruction was the complication in adenocarcinoma in 57.9% of cases, and perforation was the major local complication (47.8%) in stromal tumors. Conclusion Primary small bowel cancers are usually diagnosed at advanced stages, and revealed by a local complication of the tumor. Their surgical management in emergency setting is associated to significant morbidity and mortality rates.


RESUMO Objetivo Caracterizar o padrão de neoplasias malignas primárias do intestino delgado em um hospital terciário de Leste Europeu. Métodos Estudo retrospectivo de pacientes com câncer de intestino delgado, internados em um hospital terciário e de emergência, ao longo dos últimos 15 anos. Resultados Foram avaliados 57 pacientes com neoplasias malignas gastrintestinais, o que representou 0,039% das admissões e 0,059% das laparotomias realizadas. Total de 37 (64,9%) pacientes masculinos, média de idade de 58 anos, e de 72 anos para mulheres. Dentre os 57 pacientes, 48 (84,2%) foram internados em situação de emergência: obstrução intestinal em 21 (38,9%), perfuração em 17 (31,5%), hemorragia digestiva alta em 8 (14,8%), e hemorragia digestiva baixa em 2 (3,7%). Houve 10 (17,5%) tumores duodenais, 21 (36,8%) jejunais e 26 (45,6%) ileais. As neoplasias mais frequentes foram tumor estromal gastrintestinal, em 24 (42,1%) pacientes, adenocarcinoma em 19 (33,3%), linfoma em 8 (14%) e carcinoides em 2 (3,5%). A prevalência de adenocarcinoma duodenal foi 14,55 vezes maior do que a do intestino delgado, e a prevalência de tumores estromais duodenais foi 1,818 vez maior do que a do intestino delgado. A obstrução intestinal foi complicação do adenocarcinoma em 57,9% dos casos, e a perfuração foi a principal complicação local (47,8%) dos tumores estromais. Conclusão As neoplasias malignas primárias do intestino delgado foram geralmente diagnosticadas em estado avançado e reveladas por uma complicação local do tumor. O tratamento cirúrgico em situação de emergência está associado à significativa morbimortalidade.


Subject(s)
Adult , Aged , Aged, 80 and over , Female , Humans , Male , Middle Aged , Young Adult , Adenocarcinoma/complications , Carcinoid Tumor/complications , Gastrointestinal Hemorrhage/etiology , Gastrointestinal Stromal Tumors/complications , Intestinal Neoplasms/complications , Intestinal Obstruction/etiology , Intestinal Perforation/etiology , Adenocarcinoma/mortality , Adenocarcinoma/surgery , Carcinoid Tumor/mortality , Carcinoid Tumor/surgery , Duodenal Neoplasms/complications , Duodenal Neoplasms/mortality , Duodenal Neoplasms/surgery , Europe, Eastern , Emergency Medical Services/statistics & numerical data , Gastrointestinal Stromal Tumors/mortality , Gastrointestinal Stromal Tumors/surgery , Incidental Findings , Ileal Neoplasms/complications , Ileal Neoplasms/mortality , Ileal Neoplasms/surgery , Intestinal Neoplasms/mortality , Intestinal Neoplasms/surgery , Jejunal Neoplasms/complications , Jejunal Neoplasms/mortality , Jejunal Neoplasms/surgery , Lymphoma/complications , Lymphoma/mortality , Lymphoma/surgery , Patient Admission , Prevalence , Retrospective Studies , Tertiary Care Centers/statistics & numerical data
4.
Rev. ciênc. bioméd. (Säo Paulo) ; 14: 49-63, 1993-1994. tab, ilus
Article in Portuguese | LILACS | ID: lil-167815

ABSTRACT

Examinou-se a mortalidade por doenças do aparelho digestivo no Brasil utilizando-se dados oficiais do Ministério da Saúde, abrangendo 26 unidades da Federeçäo e 10 diferentes doenças, para os anos de 1980,1983 e 1985. As análises de Agrupamento e Componentes principais revelaram um comportamento heterogêneo entre regiöes do País, com relaçäo às 10 variáveis estudadas. Os principais elementos discriminantes foram as doenças crônicas do fígado e cirrose, as neoplasias malignas do estômago, do pâncreas, do cólon e do esôfago. Análises complementares evidenciaram uma diminuiçäo nos índices nacionais de mortalidade por doenças do aparelho digestivo, no período estudado, da ordem de 0,56 por cento, com as doenças de origem neoplásica apresentando reduçäo de 1,22 por cento e aquelas näo-neoplásicas mostrando um crescimento de 0,20 por cento. Entre as variáveis estudadas, as doenças crônicas do fígado e cirrose foram a principal causa da mortalidade no período, seguidas pelas neoplasias malignas do estômago, do esôfago, das úlceras gástricas e duodenais, das neoplasias malignas do cólon, do pâncreas, das obstruçöes intestinais sem hérnia, das neoplasias malignas do reto sigmóide/anus, das hérnias da cavidade abdominal e das apendicites. Destaque deve ser dado para os altos índices de mortalidade por neoplasias malignas do esôfago no Estado do Rio Grande do Sul


Subject(s)
Humans , Male , Female , Appendicitis/mortality , Brazil/epidemiology , Digestive System Diseases/mortality , Fibrosis/mortality , Gastrointestinal Neoplasms/mortality , Hernia, Ventral/mortality , Intestinal Neoplasms/mortality , Liver Diseases/mortality , Multivariate Analysis , Colonic Neoplasms/mortality , Intestinal Obstruction/mortality , Duodenal Ulcer/mortality , Stomach Ulcer/mortality
5.
Rev. Hosp. Clin. Fac. Med. Univ. Säo Paulo ; 48(6): 272-7, nov.-dez. 1993. tab
Article in Portuguese | LILACS | ID: lil-140090

ABSTRACT

Os linfomas colo-retais sao tumores raros e constituem 0,5 a 2 por cento das neoplasias malignas do intestino grosso e aproximadamente 10 a 20 por cento dos linfomas gastrointestinais. No Servico de Cirurgia do Colon e do Reto do Hospital das Clinicas da FMUSP foram tratados dez pacientes com linfomas colo-retais primarios nos ultimos dez anos, que corresponde a 2 por cento dos casos atendidos com neoplasias nesse mesmo periodo. A idade dos doentes variou de 22 a 76 anos, com media de 50 anos, predominando sexo masculino (8:2)...


Subject(s)
Humans , Animals , Male , Female , Adult , Intestinal Neoplasms/diagnosis , Intestinal Neoplasms/mortality , Intestinal Neoplasms/therapy , Intestine, Large/pathology , Lymphoma, Non-Hodgkin/diagnosis , Lymphoma, Non-Hodgkin/mortality , Lymphoma, Non-Hodgkin/therapy , Colonic Neoplasms/diagnosis , Colonic Neoplasms/mortality , Colonic Neoplasms/pathology , Rectal Neoplasms/diagnosis , Rectal Neoplasms/mortality , Intestinal Neoplasms/pathology , Lymphoma, Non-Hodgkin/ultrastructure , Colonic Neoplasms/therapy , Rectal Neoplasms/therapy
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